The Truth About PDGF (Ariessence) and What It Can Do for Your Skin

Innovative regenerative skin treatment now available at The Aesthetic Palace, San Diego

What makes Ariessence different in regenerative aesthetics?

Ariessence is a next-generation advancement in regenerative treatments in aesthetics, powered by platelet-derived growth factor (PDGF)—proteins clinically shown to trigger collagen production, cell growth, and vascular repair. These same growth factors have been studied for their vital role in tissue healing and have even been FDA-approved in medical wound care, including diabetic foot ulcers (Santos et al., 2024).

How is PDGF therapy better than PRP or exosomes?

Unlike PRP or exosomes, which vary in quality and depend on individual factors, Ariessence delivers a stable, pharmaceutical-grade concentration of PDGF. It’s consistent, lab-purified, and backed by science—not just hype. Research has shown that PDGF drives fibroblast activation, extracellular matrix remodeling, and angiogenesis, making it one of the most active drivers of skin regeneration (Santos et al., 2024).

Can PDGF improve the under-eye area?

Yes, and this is where Ariessence stands out. The under-eye skin is the thinnest on the body, often showing crepiness, thinning, or early aging. Ariessence helps stimulate collagen and tissue repair in this delicate area, often reducing the need for filler. The result? Tighter, smoother skin that still looks like you, just refreshed. Studies have confirmed PDGF’s impact on dermal remodeling and thickness when applied to fragile skin zones (Santos et al., 2024).

What results can I expect from Ariessence?

Used alone or paired with microneedling, RF, or laser, Ariessence helps speed up healing and enhances your results. Patients often see improved skin tone, , and firmness over several weeks as PDGF works beneath the surface to regenerate collagen and improve overall skin quality (Santos et al., 2024).

At The Aesthetic Palace in San Diego, we bring evidence-based and up-to-date practices into every treatment plan. Ariessence reflects our commitment to offering evidence-based, regenerative aesthetic solutions that respect the skin’s biology while delivering visible, lasting improvements.

References

Santos, L. C., Lana, G. L., Santos, G. S., et al. (2024). The biological role of platelet derivatives in regenerative aesthetics. International Journal of Molecular Sciences, 25(11), 5604. https://doi.org/10.3390/ijms25115604